CKDdb-logoCKDdb - Molecule ID A4542

geneABI2, ARGBPIA, ABI2B
nameAbl-interactor protein 2B
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABI2_HUMANQ9NYB9ENSG0000013844310152Hs.471156606442

Functions and classifications

GOC:cell-cell adherens junction, C:cytoskeleton, C:cytosol, C:dendrite, C:filopodium, C:lamellipodium, F:cytoskeletal adaptor activity, F:DNA binding, F:kinase binding, F:SH3 domain binding, P:actin polymerization or depolymerization, P:camera-type eye development, P:cell migration, P:dendrite development, P:learning or memory, P:peptidyl-tyrosine phosphorylation, C:cytoplasm, F:protein tyrosine kinase activator activity, P:positive regulation of protein tyrosine kinase activity
UniProt3D-structure, Alternative splicing, Cell projection, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, Phosphoprotein, Reference proteome, SH3 domain
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis) 13.6< 0.05RNA microarray  18187931
Exp18187931bMus musculus18kidneyglomeruliGlomerulonephritis (lupus nephritis) 3< 0.05RNA microarray  18187931
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.470.00077RNA microarray  19698090
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy) 0.20.004RNA microarray  25770168

Compile date 08-30-2016© iMODE-CKD consortium