CKDdb-logoCKDdb - Molecule ID A449F

geneBCL2L10, BCLB
nameApoptosis regulator Bcl-B
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:cytosol, C:integral component of membrane, C:mitochondrial outer membrane, C:nuclear membrane, F:protein heterodimerization activity, F:protein homodimerization activity, P:activation of cysteine-type endopeptidase activity involved in apoptotic process, P:extrinsic apoptotic signaling pathway in absence of ligand, P:female gamete generation, P:intrinsic apoptotic signaling pathway in response to DNA damage, P:negative regulation of apoptotic process, P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, P:negative regulation of intrinsic apoptotic signaling pathway, P:positive regulation of apoptotic process, P:spermatogenesis, C:integral to membrane, C:membrane, C:mitochondrion
UniProt3D-structure, Apoptosis, Complete proteome, Membrane, Mitochondrion, Nucleus, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.210.0000813RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium