CKDdb-logoCKDdb - Molecule ID A4432

geneCACNB2, CAVB2F, CACNLB2
nameCalcium channel
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CACB2_HUMANQ08289ENSG00000165995783Hs.59093600003, 611876

Functions and classifications

GOC:integral component of plasma membrane, C:sarcolemma, C:voltage-gated calcium channel complex, F:voltage-gated calcium channel activity, P:axon guidance, P:calcium ion import, P:neuromuscular junction development, P:positive regulation of calcium ion transport, P:synaptic transmission, P:visual perception, P:regulation of ion transmembrane transport, C:integral to plasma membrane, F:calcium channel regulator activity
UniProtAlternative splicing, Brugada syndrome, Calcium, Calcium channel, Calcium transport, Cell membrane, Complete proteome, Disease mutation, Ion channel, Ion transport, Membrane, Phosphoprotein, Polymorphism, Reference proteome, SH3 domain, Transport, Voltage-gated channel
PADBchannel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.010.04cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.210.00000582RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.310.00589RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.420.00706RNA microarray19698090
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.05< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.32< 0.05RNA microarray21752957
Exp23671862aMus musculus8heartsectionDiabetes (Diabetic Cardiomyopathy)0.59< 0.05micro-liquid chromatography system + LTQ Velos ion trap mass spectrometer23671862
Exp23671862bMus musculus8heartsectionDiabetes (Diabetic Cardiomyopathy)1.69< 0.05micro-liquid chromatography system + LTQ Velos ion trap mass spectrometer23671862

Compile date 08-10-2018© iMODE-CKD consortium