CKDdb-logoCKDdb - Molecule ID A4430

geneCACNA1S, CACH1, CACN1
nameVoltage-dependent L-type calcium channel alpha-1S subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAC1S_HUMANQ13698ENSG00000081248779Hs.1294114208, 170400, 188580, 601887

Functions and classifications

GOC:I band, C:sarcoplasmic reticulum, C:T-tubule, C:voltage-gated calcium channel complex, F:high voltage-gated calcium channel activity, F:metal ion binding, P:axon guidance, P:endoplasmic reticulum organization, P:extraocular skeletal muscle development, P:muscle contraction, P:myoblast fusion, P:neuromuscular junction development, P:skeletal muscle adaptation, P:skeletal muscle fiber development, P:skeletal system development, P:striated muscle contraction, F:voltage-gated calcium channel activity, P:regulation of ion transmembrane transport
UniProt3D-structure, Calcium, Calcium channel, Calcium transport, Complete proteome, Disease mutation, Disulfide bond, Glycoprotein, Ion channel, Ion transport, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport, Voltage-gated channel, Receptor
PADBchannel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.190.000688RNA microarray19698090
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.490.003cDNA microarray21411733

Compile date 08-10-2018© iMODE-CKD consortium