CKDdb-logoCKDdb - Molecule ID A4428

geneCACNA1H
nameVoltage-dependent T-type calcium channel alpha-1H subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAC1H_HUMANO95180ENSG000001965578912Hs.459642607904, 611942

Functions and classifications

GOC:caveola, C:sarcolemma, C:voltage-gated calcium channel complex, F:low voltage-gated calcium channel activity, F:metal ion binding, P:aldosterone biosynthetic process, P:axon guidance, P:calcium ion import, P:cellular response to hormone stimulus, P:cellular response to potassium ion, P:cortisol biosynthetic process, P:muscle contraction, P:muscle organ development, P:myoblast fusion, P:positive regulation of acrosome reaction, P:regulation of heart contraction, P:regulation of membrane potential, C:integral component of membrane, F:ion channel activity, P:ion transmembrane transport, C:integral to membrane
UniProtAlternative splicing, Calcium, Calcium channel, Calcium transport, Complete proteome, Disease mutation, Epilepsy, Glycoprotein, Ion channel, Ion transport, Membrane, Metal-binding, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport, Voltage-gated channel, Zinc
PADBchannel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.330.0000263RNA microarray19698090
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy)0.25< 0.05RNA-seq23757392
Exp23757392cRattus norvegicus18kidneywholeDiabetes (diabetic nephropathy)2.3< 0.05RNA-seq23757392
Exp24172336Mus musculus6kidneycortexAKI (AKI)20.047822241LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)2.61.25E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)7.460.012013RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium