CKDdb-logoCKDdb - Molecule ID A4423

geneBEST2, VMD2L1
nameBestrophin 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BEST2_HUMANQ8NFU1ENSG0000003998754831Hs.435611607335

Functions and classifications

GOC:chloride channel complex, C:cilium, C:plasma membrane, F:chloride channel activity, P:chloride transmembrane transport, P:membrane depolarization, P:sensory perception of smell
UniProtCalcium, Cell membrane, Chloride, Chloride channel, Complete proteome, Ion channel, Ion transport, Membrane, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBchannel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.210.000881RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.35< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium