CKDdb-logoCKDdb - Molecule ID A437F

geneADAMTS20
nameA disintegrin and metalloproteinase with thrombospondin motifs 20
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATS20_HUMANP59510ENSG0000017315780070Hs.287554611681

Functions and classifications

GOC:extracellular space, C:proteinaceous extracellular matrix, F:metalloendopeptidase activity, F:zinc ion binding, P:extracellular matrix organization, P:negative regulation of apoptotic process, P:positive regulation of melanocyte differentiation, P:positive regulation of signal transduction, P:proteolysis, F:metal ion binding
UniProtAlternative splicing, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, Extracellular matrix, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Repeat, Secreted, Signal, Zinc, Zymogen
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.341.10E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium