CKDdb-logoCKDdb - Molecule ID A4370

genePPIB, CYPB
namePeptidyl-prolyl cis-trans isomerase B precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PPIB_HUMANP23284ENSG000001667945479Hs.434937123841, 259440

Functions and classifications

GOC:endoplasmic reticulum lumen, C:melanosome, F:peptide binding, F:peptidyl-prolyl cis-trans isomerase activity, F:unfolded protein binding, P:extracellular matrix organization, P:protein folding
UniProt3D-structure, Complete proteome, Cyclosporin, Direct protein sequencing, Disease mutation, Dwarfism, Endoplasmic reticulum, Glycoprotein, Isomerase, Osteogenesis imperfecta, Polymorphism, Reference proteome, Rotamase, Signal
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)3.060.00000101RNA microarray19698090
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection)0.3 LC-MS/MS20543976
Exp20940332Mus musculus kidneycollecting duct cellsVasopressine_induced (Vasopressine in vitro model)0.81< 0.05LC-MS/MS20940332
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.95< 0.05RNA microarray21752957
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)5.42< 0.05RNA microarray21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.380.033863104LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium