CKDdb-logoCKDdb - Molecule ID A436F

geneATOH1, ATH1, BHLHA14
nameAtonal protein homolog 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATOH1_HUMANQ92858ENSG00000172238474Hs.532680601461

Functions and classifications

GOC:nucleus, F:chromatin DNA binding, F:sequence-specific DNA binding, F:sequence-specific DNA binding transcription factor activity, P:auditory receptor cell fate determination, P:auditory receptor cell fate specification, P:axon guidance, P:central nervous system development, P:cerebral cortex development, P:inner ear morphogenesis, P:negative regulation of apoptotic process, P:neuron migration, P:positive regulation of auditory receptor cell differentiation, P:positive regulation of neuron differentiation, P:positive regulation of transcription from RNA polymerase II promoter, P:transcription from RNA polymerase II promoter, P:apoptotic process
UniProtActivator, Complete proteome, Developmental protein, Differentiation, DNA-binding, Neurogenesis, Nucleus, Polymorphism, Reference proteome, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.380.00503RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.311.60E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium