CKDdb-logoCKDdb - Molecule ID A4274

geneBAG5
nameBAG-family molecular chaperone regulator-5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BAG5_HUMANQ9UL15ENSP000002992049529Hs.5443603885

Functions and classifications

GOC:inclusion body, C:perinuclear region of cytoplasm, F:ubiquitin protein ligase binding, P:negative regulation of protein refolding, P:negative regulation of ubiquitin-protein ligase activity, P:neuron death, P:protein folding, P:regulation of inclusion body assembly
UniProt3D-structure, Alternative splicing, Chaperone, Complete proteome, Polymorphism, Reference proteome, Repeat
PADBCHA: chaperone, chaperonin

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.34< 0.05RNA microarray21752957
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.357.49E-04RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.250.011125RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium