CKDdb-logoCKDdb - Molecule ID A4271

geneATOX1, HAH1
nameCopper transport protein ATOX1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATOX1_HUMANO00244ENSP00000316854475Hs.125213602270

Functions and classifications

GOC:cytosol, F:copper chaperone activity, P:cellular copper ion homeostasis, P:copper ion transport, P:response to oxidative stress, F:metal ion binding, P:metal ion transport, F:copper ion binding
UniProt3D-structure, Chaperone, Complete proteome, Copper, Copper transport, Ion transport, Metal-binding, Reference proteome, Transport
PADBCHA: chaperone, chaperonin

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)2.38< 0.05LC-MS/MS19845401
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.31< 0.05RNA microarray21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.730.014321334LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.413.77E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium