CKDdb-logoCKDdb - Molecule ID A4268

geneAHSA1, HSPC322
nameActivator of 90 kDa heat shock protein ATPase homolog 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AHSA1_HUMANO95433ENSP0000021647910598Hs.204041608466

Functions and classifications

GOC:cytoplasm, C:cytosol, C:endoplasmic reticulum, F:ATPase activator activity, F:chaperone binding, P:response to stress, P:positive regulation of ATPase activity, P:protein folding
UniProt3D-structure, Acetylation, Chaperone, Complete proteome, Cytoplasm, Endoplasmic reticulum, Phosphoprotein, Reference proteome, Stress response
PADBCHA: chaperone, chaperonin

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18354378Homo sapiens8kidneyepithelial cellsureteral_obstruction (unilateral ureteral obstruction)4.408 +/- 1.189< 0.05RNA microarray18354378
Exp19688724Mus musculus kidneypodocytesHigh_glucose_induced (High glucose in vitro model)0< 0.05MALDI-TOF-MS19688724
Exp20940332Mus musculus kidneycollecting duct cellsVasopressine_induced (Vasopressine in vitro model)0.76< 0.05LC-MS/MS20940332
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.049762673LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium