CKDdb-logoCKDdb - Molecule ID A410F

geneACCN3, ASIC3, SLNAC1
nameAmiloride-sensitive cation channel 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ASIC3_HUMANQ9UHC3ENSG000002131999311Hs.647113611741

Functions and classifications

GOC:cytoplasm, C:integral component of plasma membrane, F:enterobactin transporter activity, F:ligand-gated sodium channel activity, F:sodium channel activity, P:detection of chemical stimulus involved in sensory perception of pain, P:detection of mechanical stimulus involved in sensory perception of pain, P:detection of temperature stimulus involved in sensory perception of pain, P:response to acid, P:response to heat, P:sensory perception, P:signal transduction, C:integral component of membrane, P:sodium ion transmembrane transport, C:integral to plasma membrane, C:integral to membrane
UniProtAlternative splicing, Cell membrane, Complete proteome, Cytoplasm, Disulfide bond, Glycoprotein, Ion channel, Ion transport, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Sodium, Sodium channel, Sodium transport, Transmembrane, Transmembrane helix, Transport
PADBchannel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.260.000208RNA microarray  19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI) 10000.0062007LC-MS/MS  24172336

Compile date 08-30-2016© iMODE-CKD consortium