CKDdb-logoCKDdb - Molecule ID A408F

geneAsh2l
nameSet1/Ash2 histone methyltransferase complex subunit ASH2
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ASH2L_MOUSEQ91X20ENSMUSG0000003157523808Mm.27706

Functions and classifications

GOC:histone methyltransferase complex, C:MLL1 complex, C:nucleus, C:Set1C/COMPASS complex, F:histone methyltransferase activity (H3-K4 specific), F:metal ion binding, F:protein binding, F:transcription regulatory region DNA binding, P:cellular response to DNA damage stimulus, P:histone H3-K4 methylation, P:positive regulation of cell proliferation, P:positive regulation of transcription from RNA polymerase II promoter, P:response to estrogen, P:transcription, DNA-templated, C:histone methyltransferase complex, C:nucleus, F:protein binding, P:cellular response to DNA damage stimulus, P:positive regulation of transcription from RNA polymerase II promoter, C:histone methyltransferase complex, C:nucleus, C:Set1C/COMPASS complex, F:histone methyltransferase activity (H3-K4 specific), F:protein binding, F:transcription regulatory region DNA binding, P:cellular response to DNA damage stimulus, P:positive regulation of cell proliferation, P:positive regulation of transcription from RNA polymerase II promoter, P:response to estrogen, C:histone methyltransferase complex, C:nucleus, F:protein binding, P:cellular response to DNA damage stimulus, P:positive regulation of transcription from RNA polymerase II promoter, C:histone methyltransferase complex, C:nucleus, F:protein binding, P:cellular response to DNA damage stimulus, P:positive regulation of transcription from RNA polymerase II promoter, C:histone methyltransferase complex, C:nucleus, C:Set1C/COMPASS complex, F:histone methyltransferase activity (H3-K4 specific), F:protein binding, F:transcription regulatory region DNA binding, P:cellular response to DNA damage stimulus, P:positive regulation of cell proliferation, P:positive regulation of transcription from RNA polymerase II promoter, P:response to estrogen, C:histone methyltransferase complex, C:nucleus, F:protein binding, P:cellular response to DNA damage stimulus, P:positive regulation of transcription from RNA polymerase II promoter, C:histone methyltransferase complex, C:nucleus, F:protein binding, P:cellular response to DNA damage stimulus, P:positive regulation of transcription from RNA polymerase II promoter
UniProtChromatin regulator, Complete proteome, DNA-binding, Metal-binding, Methylation, Nucleus, Phosphoprotein, Reference proteome, Transcription, Transcription regulation, Zinc, Zinc-finger
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp24569379Mus musculuskidneyendothelial cellsAKI (AKI)0.440.000000222RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium