CKDdb-logoCKDdb - Molecule ID A406F

geneASF1A, CGI-98, HSPC146
nameHistone chaperone ASF1A
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ASF1A_HUMANQ9Y294ENSP0000022959525842Hs.292316609189

Functions and classifications

GOC:nucleus, F:chromatin binding, F:histone binding, P:chromatin modification, P:DNA repair, P:muscle cell differentiation, P:negative regulation of chromatin silencing, P:nucleosome assembly, P:osteoblast differentiation, P:transcription, DNA-templated, C:chromatin remodeling complex, P:transcription, DNA-dependent, C:nucleus, P:chromatin assembly or disassembly
UniProt3D-structure, Chaperone, Chromatin regulator, Complete proteome, Nucleus, Phosphoprotein, Reference proteome, Transcription, Transcription regulation
PADBCHA: chaperone, chaperonin

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.293.23E-06RNA microarray20019191
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.336.14E-04RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.330.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium