CKDdb-logoCKDdb - Molecule ID A4069

geneCABL1, CABLES1, CABLES
nameCDK5 and ABL1 enzyme substrate 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CABL1_HUMANQ8TDN4ENSG0000013450891768Hs.11108609194

Functions and classifications

GOC:cytosol, C:nucleus, F:cyclin-dependent protein serine/threonine kinase regulator activity, P:blood coagulation, P:cell cycle, P:cell division, P:nervous system development, P:regulation of cell cycle, P:regulation of cell division, P:regulation of protein kinase activity, F:cyclin-dependent protein kinase regulator activity
UniProtAlternative splicing, Cell cycle, Cell division, Complete proteome, Cyclin, Cytoplasm, Nucleus, Phosphoprotein, Reference proteome
PADBcell cycle (turnover, mitosis, meiosis)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.382.28E-18NGS, RNA-seq.22266139
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)0.770cDNA microarray23505438
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.530.043478913LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.482.42E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium