CKDdb-logoCKDdb - Molecule ID A3946

geneAbcd3, Pmp70, Pxmp1
nameATP-binding cassette sub-family D member 3
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCD3_MOUSEP55096ENSMUSG0000002812719299Mm.399042170995

Functions and classifications

GOC:integral component of membrane, C:mitochondrial inner membrane, C:mitochondrion, C:peroxisomal matrix, C:peroxisomal membrane, C:peroxisome, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:protein binding, P:fatty acid beta-oxidation, P:peroxisome organization, P:very long-chain fatty acid catabolic process, C:integral to membrane, P:response to drug, P:ATP catabolic process, F:ATPase activity
UniProtAcetylation, ATP-binding, Complete proteome, Glycoprotein, Membrane, Nucleotide-binding, Peroxisome, Phosphoprotein, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp17579666bMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model) 0.250.05RNA microarray  17579666
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.480.01cDNA microarray  19099603
Exp24172336Mus musculus6kidneycortexAKI (AKI) 1.650.009265956LC-MS/MS  24172336
Exp24927646aMus musculus16kidney Diabetes (diabetic nephropathy treated with Phlorizin) 0.93< 0.05LC-MS/MS  24927646
Exp24927646bMus musculus16kidney Diabetes (diabetic nephropathy) 0.54< 0.05LC-MS/MS  24927646
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 0.130.013999RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium