CKDdb-logoCKDdb - Molecule ID A3884

geneNCAM1, NCAM
nameNeural cell adhesion molecule 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
NCAM1_HUMANP13591ENSG000001492944684Hs.503878116930

Functions and classifications

GOC:anchored component of membrane, C:external side of plasma membrane, C:extracellular region, C:Golgi membrane, C:integral component of membrane, P:axon guidance, P:cell adhesion, P:extracellular matrix organization, P:interferon-gamma-mediated signaling pathway, C:membrane, C:anchored to membrane, C:axon, C:growth cone, C:integral to membrane, C:neuronal cell body, P:homotypic cell-cell adhesion, P:positive regulation of calcium-mediated signaling, P:regulation of exocyst assembly, P:cell surface receptor signaling pathway, P:neuron projection development
UniProt3D-structure, Alternative splicing, Cell adhesion, Cell membrane, Complete proteome, Disulfide bond, Glycoprotein, GPI-anchor, Immunoglobulin domain, Lipoprotein, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Secreted, Signal, Transmembrane, Transmembrane helix
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17183245Homo sapiens24kidneyproximal tubuleproteinuria (proteinuric nephropathies)0.13< 0.05cDNA microarrays17183245
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.230.000605RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.380.000283RNA microarray19698090
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection)0.2 LC-MS/MS20543976
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection)0.2 LC-MS/MS20543976
Exp21544065cRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)80.003MALDI-TOF/TOF21544065
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.32< 0.05RNA-seq23757392
Exp24096133bHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy)1000 1DE, MALDI24096133
Exp24096133dHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy vs type 1 diabetes without retinopathy or nephropathy)1000 1DE, MALDI24096133
Exp24096133fHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes with retinopathy)0 1DE, MALDI24096133
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.322.87E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium