CKDdb-logoCKDdb - Molecule ID A3881

geneADAM23, MDC3
nameADAM 23 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA23_HUMANO75077ENSG000001149488745Hs.370287603710

Functions and classifications

GOC:extracellular region, C:integral component of plasma membrane, F:integrin binding, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:cell adhesion, P:central nervous system development, P:proteolysis, P:integrin-mediated signaling pathway, C:integral to plasma membrane, F:metal ion binding
UniProtAlternative splicing, Cell adhesion, Cell membrane, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Membrane, Reference proteome, Secreted, Signal, Transmembrane, Transmembrane helix, Integrin, Hydrolase, Metal-binding, Metalloprotease, Protease
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)3.040.0204493RNA microarray19698090
Exp21411733aMus musculus13macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)3.910cDNA microarray21411733
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)2.320.0308723RNA microarray23935909

Compile date 08-10-2018© iMODE-CKD consortium