CKDdb-logoCKDdb - Molecule ID A382F

geneARNT2, BHLHE1
nameAryl hydrocarbon receptor nuclear translocator 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARNT2_HUMANQ9HBZ2ENSG000001723799915Hs.459070606036

Functions and classifications

GOC:cytoplasm, C:nucleus, C:transcription factor complex, F:aryl hydrocarbon receptor binding, F:DNA binding, F:protein heterodimerization activity, F:sequence-specific DNA binding transcription factor activity, F:signal transducer activity, P:central nervous system development, P:in utero embryonic development, P:negative regulation of apoptotic process, P:positive regulation of cell proliferation, P:positive regulation of transcription from RNA polymerase II promoter, P:positive regulation of transcription, DNA-templated, P:response to estradiol, P:response to hypoxia, P:transcription, DNA-templated, C:cytoplasm, P:positive regulation of transcription, DNA-dependent, P:response to estradiol stimulus, P:transcription, DNA-dependent
UniProtAlternative splicing, Complete proteome, DNA-binding, Nucleus, Polymorphism, Reference proteome, Repeat, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.260.00158RNA microarray19698090
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.340.027806886NGS, RNA-seq.22266139
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.03< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium