CKDdb-logoCKDdb - Molecule ID A3782

geneAifm3, Aifl
nameApoptosis-inducing factor 3
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
AIFM3_MOUSEQ3TY86ENSMUSG0000002276372168Mm.40038

Functions and classifications

GOC:endoplasmic reticulum, C:mitochondrial inner membrane, C:mitochondrion, F:2 iron, 2 sulfur cluster binding, F:flavin adenine dinucleotide binding, F:metal ion binding, F:oxidoreductase activity, P:cell redox homeostasis, P:execution phase of apoptosis, F:cysteine-type endopeptidase activator activity involved in apoptotic process, P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c, P:electron transport chain, P:induction of apoptosis, P:mitochondrial depolarization
UniProt2Fe-2S, Alternative splicing, Apoptosis, Complete proteome, Electron transport, FAD, Flavoprotein, Iron, Iron-sulfur, Metal-binding, Mitochondrion, Oxidoreductase, Reference proteome, Transport
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.50.03cDNA microarray19099603

Compile date 08-10-2018© iMODE-CKD consortium