CKDdb-logoCKDdb - Molecule ID A3713

geneCBR4
nameCarbonic reductase 4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
CBR4_HUMANQ8N4T8ENSG0000014543984869Hs.659311

Functions and classifications

GOC:mitochondrial matrix, F:NAD(P)H dehydrogenase (quinone) activity, F:NADPH binding, F:NADPH dehydrogenase (quinone) activity, F:quinone binding, P:daunorubicin metabolic process, P:doxorubicin metabolic process, P:fatty acid biosynthetic process, P:protein homotetramerization, F:oxidoreductase activity, P:oxidation-reduction process, F:nucleotide binding
UniProtAcetylation, Alternative splicing, Complete proteome, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mitochondrion, NAD, NADP, Oxidoreductase, Polymorphism, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.410.0272RNA microarray19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI)3.720.041312596LC-MS/MS24172336
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.50.00000651RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium