CKDdb-logoCKDdb - Molecule ID A370F

geneARHGEF25, GEFT, SLC26A10
nameGuanine nucleotide exchange factor GEFT
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARHGP_HUMANQ86VW2ENSG00000240771115557Hs.61581610215

Functions and classifications

GOC:cytosol, C:myofibril, C:plasma membrane, C:sarcomere, F:Rho guanyl-nucleotide exchange factor activity, P:regulation of Rho GTPase activity, F:protein serine/threonine kinase activity, P:protein phosphorylation, F:phospholipid binding, P:regulation of Rho protein signal transduction, C:intracellular
UniProt3D-structure, Alternative splicing, Cell membrane, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Polymorphism, Reference proteome
PADBMOD: modulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)5.471.50E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium