CKDdb-logoCKDdb - Molecule ID A3702

geneBdh1, Bdh
nameD-beta-hydroxybutyrate dehydrogenase, mitochondrial
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BDH_MOUSEQ80XN0ENSMUSG0000004659871911Mm.293470603063

Functions and classifications

GOC:mitochondrial inner membrane, C:mitochondrial matrix, C:mitochondrion, C:nucleus, F:3-hydroxybutyrate dehydrogenase activity, F:phospholipid binding, P:adipose tissue development, P:brain development, P:liver development, P:response to cadmium ion, P:response to corticosterone, P:response to drug, P:response to estradiol, P:response to ethanol, P:response to growth hormone, P:response to insulin, P:response to nutrient, P:response to starvation, P:response to toxic substance, C:mitochondrial inner membrane, C:mitochondrion, F:oxidoreductase activity
UniProtAcetylation, Allosteric enzyme, Complete proteome, Direct protein sequencing, Mitochondrion, NAD, Oxidoreductase, Reference proteome, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.470.01cDNA microarray19099603
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.370.00176RNA microarray24569379
Exp24927646aMus musculus16kidney Diabetes (diabetic nephropathy treated with Phlorizin)0.62< 0.05LC-MS/MS24927646
Exp24927646bMus musculus16kidney Diabetes (diabetic nephropathy)0.4< 0.05LC-MS/MS24927646

Compile date 08-10-2018© iMODE-CKD consortium