CKDdb-logoCKDdb - Molecule ID A3694

geneAcat1
nameAcetyl-CoA acetyltransferase, mitochondrial
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
THIL_MOUSEQ8QZT1ENSMUSG00000032047110446Mm.293233203750, 607809

Functions and classifications

GOC:mitochondrial inner membrane, C:mitochondrial matrix, C:mitochondrion, F:acetyl-CoA C-acetyltransferase activity, F:coenzyme binding, F:metal ion binding, P:adipose tissue development, P:brain development, P:liver development, P:metanephric proximal convoluted tubule development, P:protein homooligomerization, P:response to hormone, P:response to organic cyclic compound, P:response to starvation, C:mitochondrial inner membrane, C:mitochondrion, F:acetyl-CoA C-acetyltransferase activity
UniProtAcetylation, Acyltransferase, Complete proteome, Direct protein sequencing, Metal-binding, Mitochondrion, Potassium, Reference proteome, Transferase, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.28< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.82< 0.05cDNA microarray17003339
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.390.01cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.360cDNA microarray19099603
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.393.23E-06RNA microarray20019191
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp20348205aRattus norvegicus10bloodplasmaDiabetes (Gestational Diabetes)0.85< 0.01RP-nano-LC-ESI-MS/MS20348205
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.480.000395RNA microarray24569379
Exp24726496Rattus norvegicus kidneyglomeruliDiabetes (diabetic nephropathy)  LC-MS/MS24726496

Compile date 08-10-2018© iMODE-CKD consortium