CKDdb-logoCKDdb - Molecule ID A367F

geneARHGEF40, SOLO
nameRho guanine nucleotide exchange factor 40
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARH40_HUMANQ8TER5ENSP0000029869355701Hs.35125610018

Functions and classifications

GOC:cytoplasm, F:Rho guanyl-nucleotide exchange factor activity, P:regulation of Rho GTPase activity, F:phospholipid binding, P:regulation of Rho protein signal transduction, C:intracellular
UniProtAlternative splicing, Coiled coil, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Phosphoprotein, Polymorphism, Reference proteome
PADBMOD: modulator, regulator

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.22< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.35< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium