CKDdb-logoCKDdb - Molecule ID A363F

geneARAP2, CENTD1
nameArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARAP2_HUMANQ8WZ64ENSP00000302895116984Hs.479451606645

Functions and classifications

GOC:cytosol, F:ARF GTPase activator activity, F:phosphatidylinositol-3,4,5-trisphosphate binding, F:zinc ion binding, P:positive regulation of GTPase activity, P:regulation of ARF GTPase activity, P:regulation of small GTPase mediated signal transduction, P:small GTPase mediated signal transduction, C:intracellular, P:signal transduction, F:GTPase activator activity, F:metal ion binding, F:phospholipid binding
UniProt3D-structure, Complete proteome, Cytoplasm, GTPase activation, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Zinc, Zinc-finger
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.96< 0.05RNA microarray21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.049762673LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.469.50E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium