CKDdb-logoCKDdb - Molecule ID A3599

geneALDH1B1, ALDH5, ALDHX
nameAldehyde dehydrogenase X
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AL1B1_HUMANP30837ENSG00000137124219Hs.436219100670

Functions and classifications

GOC:mitochondrial matrix, C:mitochondrion, C:nucleus, F:aldehyde dehydrogenase (NAD) activity, P:carbohydrate metabolic process, P:ethanol catabolic process, C:mitochondrion, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
UniProtAcetylation, Complete proteome, Mitochondrion, NAD, Oxidoreductase, Polymorphism, Reference proteome, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.40.0237461RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.470.026RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.488.81E-05RNA microarray20019191
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.34< 0.05RNA microarray21752957
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.06< 0.05RNA-seq23757392
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy)0.09< 0.05RNA-seq23757392
Exp25279147Homo sapiens12kidneybiopsy sectionGlomerulonephritis (IgA nephropathy)0.44< 0.05MALDI TOF/TOF25279147

Compile date 08-10-2018© iMODE-CKD consortium