CKDdb-logoCKDdb - Molecule ID A354D

geneAMER2, FAM123A
nameAPC membrane recruitment protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMER2_HUMANQ8N7J2ENSG00000165566219287Hs.528335614659

Functions and classifications

GOC:plasma membrane, F:phosphatidylinositol-4,5-bisphosphate binding, P:ectoderm development, P:negative regulation of canonical Wnt signaling pathway, P:Wnt signaling pathway, P:negative regulation of canonical Wnt receptor signaling pathway, P:Wnt receptor signaling pathway"
UniProtAlternative splicing, Cell membrane, Complete proteome, Lipid-binding, Membrane, Phosphoprotein, Polymorphism, Reference proteome, Wnt signaling pathway
PADBSIG: signalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.311.02E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.180.01509RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium