CKDdb-logoCKDdb - Molecule ID A3514

nameARF-GAP with GTPase
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:mitochondrion, C:nucleolus, F:ARF GTPase activator activity, F:GTP binding, F:zinc ion binding, P:axon guidance, P:negative regulation of neuron apoptotic process, P:negative regulation of protein catabolic process, P:positive regulation of GTPase activity, P:protein transport, P:regulation of ARF GTPase activity, P:small GTPase mediated signal transduction, C:nucleus, F:protein kinase activator activity, P:mammary gland alveolus development, P:negative regulation of apoptotic process, P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, P:positive regulation of JAK-STAT cascade, P:positive regulation of mammary gland epithelial cell proliferation, P:positive regulation of transcription from RNA polymerase II promoter, C:intracellular, F:metal ion binding, F:phospholipid binding, C:cytosol, P:positive regulation of protein kinase activity
UniProt3D-structure, Alternative splicing, ANK repeat, Complete proteome, Cytoplasm, GTP-binding, GTPase activation, Metal-binding, Nucleotide-binding, Nucleus, Phosphoprotein, Polymorphism, Protein transport, Reference proteome, Repeat, Transport, Tumor suppressor, Zinc, Zinc-finger
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.440.0274RNA microarray19698090
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.230.014395RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium