CKDdb-logoCKDdb - Molecule ID A349J

geneAkr1c21
nameAldo-keto reductase family 1 member C21
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
AK1CL_MOUSEQ91WR5ENSMUSG0000002120777337Mm.27085

Functions and classifications

GOC:cytoplasm, F:aldo-keto reductase (NADP) activity, F:androsterone dehydrogenase activity, F:steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, P:steroid biosynthetic process
UniProt3D-structure, Complete proteome, Cytoplasm, Lipid metabolism, NADP, Oxidoreductase, Reference proteome, Steroid metabolism
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)0.22< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)0.2< 0.05cDNA microarray17003339
Exp17579666aMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)0.370.05RNA microarray17579666
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.360.02cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.120.03cDNA microarray19099603

Compile date 08-10-2018© iMODE-CKD consortium