CKDdb-logoCKDdb - Molecule ID A3476

geneCACNB3, CACNLB3
nameVoltage-dependent L-type calcium channel beta-3 subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CACB3_HUMANP54284ENSP00000301050784Hs.250712601958

Functions and classifications

GOC:apical plasma membrane, C:cytosol, C:voltage-gated calcium channel complex, F:voltage-gated calcium channel activity, P:axon guidance, P:membrane depolarization, P:synaptic transmission, P:T cell receptor signaling pathway, P:regulation of ion transmembrane transport
UniProtAlternative splicing, Calcium, Calcium channel, Calcium transport, Complete proteome, Ion channel, Ion transport, Polymorphism, Reference proteome, SH3 domain, Transport, Voltage-gated channel
PADBCNL: channel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.08< 0.05RNA microarray21752957
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.13< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium