CKDdb-logoCKDdb - Molecule ID A3471

geneCACNA1E, CACH6, CACNL1A6
nameVoltage-dependent R-type calcium channel alpha-1E subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAC1E_HUMANQ15878ENSG00000198216777Hs.437444601013

Functions and classifications

GOC:voltage-gated calcium channel complex, F:calcium ion binding, F:voltage-gated calcium channel activity, P:energy reserve metabolic process, P:membrane depolarization, P:regulation of insulin secretion, P:small molecule metabolic process, P:synaptic transmission, P:regulation of ion transmembrane transport, F:metal ion binding
UniProt3D-structure, Alternative splicing, Calcium, Calcium channel, Calcium transport, Complete proteome, Disulfide bond, Glycoprotein, Ion channel, Ion transport, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport, Voltage-gated channel
PADBchannel

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.370.000853RNA microarray19698090
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)7.40.013159RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium