CKDdb-logoCKDdb - Molecule ID A3466

geneATP2B3, PMCA3A
namePlasma membrane calcium-transporting ATPase 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AT2B3_HUMANQ16720ENSG00000067842492Hs.533956300014, 302500

Functions and classifications

GOC:integral component of membrane, C:plasma membrane, F:ATP binding, F:calcium-transporting ATPase activity, F:metal ion binding, P:blood coagulation, P:cell death, P:ATP catabolic process, P:calcium ion transmembrane transport, C:integral to membrane, P:ATP biosynthetic process
UniProtAlternative splicing, ATP-binding, Calcium, Calcium transport, Calmodulin-binding, Cell membrane, Complete proteome, Disease mutation, Hydrolase, Ion transport, Magnesium, Membrane, Metal-binding, Neurodegeneration, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.420.00464RNA microarray19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.670.049147423LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium