CKDdb-logoCKDdb - Molecule ID A343J

geneApobec3
nameDNA dC->dU-editing enzyme APOBEC-3
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ABEC3_MOUSEQ99J72ENSMUSG0000000958580287Mm.284059

Functions and classifications

GOC:cytoplasm, F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines, F:protein binding, F:zinc ion binding, P:defense response to virus, P:hematopoietic progenitor cell differentiation, P:innate immune response, P:negative regulation of transposition, P:negative regulation of viral genome replication, F:metal ion binding, P:metabolic process, C:cytoplasmic mRNA processing body, C:nucleus, F:cytidine deaminase activity, P:DNA cytosine deamination, P:negative regulation of single stranded viral RNA replication via double stranded DNA intermediate, P:negative regulation of retroviral genome replication
UniProtAlternative splicing, Antiviral defense, Complete proteome, Cytoplasm, Hydrolase, Immunity, Innate immunity, Metal-binding, Polymorphism, Reference proteome, Repeat, Zinc, Lipoprotein
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis)7.8< 0.05RNA microarray18187931
Exp18187931bMus musculus18kidneyglomeruliGlomerulonephritis (lupus nephritis)2.7< 0.05RNA microarray18187931
Exp19099603bMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.320.01cDNA microarray19099603
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)6.070.03cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)4.370cDNA microarray19099603
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)3.91< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium