CKDdb-logoCKDdb - Molecule ID A3413

geneAlx1
nameALX homeobox protein 1
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALX1_RATQ63087ENSRNOG0000000439025401Rn.9282601527, 613456

Functions and classifications

GOC:nucleus, C:transcription factor complex, F:sequence-specific DNA binding, F:sequence-specific DNA binding transcription factor activity, P:anterior/posterior pattern specification, P:embryonic limb morphogenesis, P:embryonic skeletal system morphogenesis, P:mesenchymal cell development, P:negative regulation of transcription from RNA polymerase II promoter, P:neural tube closure, P:palate development, P:positive regulation of transcription from RNA polymerase II promoter, P:positive regulation of transcription, DNA-templated, P:skeletal system development, P:transcription, DNA-templated, P:positive regulation of transcription, DNA-dependent, P:transcription, DNA-dependent
UniProtAcetylation, Activator, Complete proteome, Developmental protein, DNA-binding, Homeobox, Nucleus, Reference proteome, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.19< 0.05RNA-seq23757392
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy)0.20.005RNA microarray25770168

Compile date 08-10-2018© iMODE-CKD consortium