CKDdb-logoCKDdb - Molecule ID A3412

geneALX4
nameHomeobox protein aristaless-like 4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALX4_HUMANQ9H161ENSG0000005285060529Hs.436055601224, 605420, 609597, 613451

Functions and classifications

GOC:nucleus, C:transcription factor complex, F:DNA binding, F:sequence-specific DNA binding, F:sequence-specific DNA binding transcription factor activity, P:anterior/posterior pattern specification, P:digestive tract development, P:embryonic digit morphogenesis, P:embryonic forelimb morphogenesis, P:embryonic hindlimb morphogenesis, P:embryonic skeletal system morphogenesis, P:hair follicle development, P:muscle organ development, P:palate development, P:positive regulation of transcription from RNA polymerase II promoter, P:post-embryonic development, P:regulation of apoptotic process, P:skeletal system development, P:transcription, DNA-templated, P:transcription, DNA-dependent
UniProt3D-structure, Activator, Complete proteome, Craniosynostosis, Developmental protein, Disease mutation, DNA-binding, Homeobox, Nucleus, Polymorphism, Reference proteome, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.430.00889RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium