CKDdb-logoCKDdb - Molecule ID A3226

geneBCL11A, CTIP1, EVI9
nameB-cell lymphoma/leukemia 11A
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BC11A_HUMANQ9H165ENSG0000011986653335Hs.370549142335, 606557

Functions and classifications

GOC:cytoplasm, C:nucleus, F:metal ion binding, F:nucleic acid binding, F:protein homodimerization activity, F:transcription corepressor activity, P:B cell differentiation, P:hemopoiesis, P:negative regulation of axon extension, P:negative regulation of collateral sprouting, P:negative regulation of dendrite development, P:negative regulation of gene expression, P:negative regulation of protein homooligomerization, P:positive regulation of collateral sprouting, P:positive regulation of neuron projection development, P:positive regulation of transcription from RNA polymerase II promoter, P:protein sumoylation, P:regulation of dendrite development, P:regulation of transcription, DNA-templated, P:T cell differentiation, P:transcription, DNA-templated, P:regulation of RNA biosynthetic process, C:nuclear body, F:zinc ion binding, P:regulation of transcription, DNA-dependent, P:transcription, DNA-dependent, C:intracellular
UniProtAlternative splicing, Chromosomal rearrangement, Complete proteome, Cytoplasm, Isopeptide bond, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Repressor, Transcription, Transcription regulation, Ubl conjugation, Zinc, Zinc-finger
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.280.000000865RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.380.000112RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.460.00708RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.342.10E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.150.013999RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.150.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium