CKDdb-logoCKDdb - Molecule ID A3225

geneBcl11b
nameB-cell leukemia/lymphoma 11B (Predicted), isoform CRA_a
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BC11B_HUMAND4A0W4ENSRNOG00000005776314423Rn.162897606558

Functions and classifications

GOC:nucleus, F:metal ion binding, F:RNA polymerase II core promoter proximal region sequence-specific DNA binding, F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, P:alpha-beta T cell differentiation, P:epithelial cell morphogenesis, P:keratinocyte development, P:negative regulation of apoptotic process, P:negative regulation of cell proliferation, P:odontogenesis of dentin-containing tooth, P:olfactory bulb axon guidance, P:positive T cell selection, P:post-embryonic camera-type eye development, P:regulation of keratinocyte proliferation, P:regulation of lipid metabolic process, P:regulation of neuron differentiation, P:striatal medium spiny neuron differentiation, P:T cell differentiation in thymus, P:T cell receptor V(D)J recombination, P:thymus development, C:intracellular, F:nucleic acid binding, F:zinc ion binding, P:axonogenesis, P:skin development
UniProtComplete proteome, Reference proteome
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)3.2< 0.05RNA-seq23757392
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.270.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium