CKDdb-logoCKDdb - Molecule ID A320H

geneBCDIN3, MEPCE
name7SK snRNA methylphophate capping enzyme
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MEPCE_HUMANQ7L2J0ENSG0000014683456257Hs.178011611478

Functions and classifications

GOF:RNA methyltransferase activity, F:S-adenosylmethionine-dependent methyltransferase activity, P:negative regulation of chromatin binding, P:negative regulation of transcription from RNA polymerase II promoter, P:positive regulation of G1/S transition of mitotic cell cycle, P:snRNA modification, F:methyltransferase activity, P:methylation
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Methyltransferase, Phosphoprotein, Reference proteome, S-adenosyl-L-methionine, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.460.0000308RNA microarray19698090
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)5.290.010687RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium