CKDdb-logoCKDdb - Molecule ID A304I

geneXtrp2, Slc6a18
nameSodium-dependent neutral amino acid transporter B(0)AT3
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
S6A18_RATQ62687ENSRNOG0000001625329323Rn.9998

Functions and classifications

GOC:integral component of plasma membrane, F:neurotransmitter:sodium symporter activity, P:amino acid transport, P:hyperosmotic response, P:response to osmotic stress, C:integral to plasma membrane, C:integral component of plasma membrane, F:neurotransmitter:sodium symporter activity, C:integral to plasma membrane, C:integral component of plasma membrane, F:neurotransmitter:sodium symporter activity, C:integral to plasma membrane, C:integral to plasma membrane, F:neurotransmitter:sodium symporter activity, C:integral to plasma membrane, F:neurotransmitter:sodium symporter activity, C:integral to plasma membrane, F:neurotransmitter:sodium symporter activity
UniProtAmino-acid transport, Complete proteome, Glycoprotein, Membrane, Neurotransmitter transport, Reference proteome, Symport, Transmembrane, Transmembrane helix, Transport, Complete proteome, Membrane, Reference proteome, Symport, Transmembrane, Transmembrane helix, Transport, , , ,
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.410.03cDNA microarray19099603
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.120.000223RNA microarray23291264
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.260.000689RNA microarray23291264
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.32 nLC-ESI-UHR-QToF-MS/MS23344851
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.49< 0.05RNA-seq23757392
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.290.006797096LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium