CKDdb-logoCKDdb - Molecule ID A286F

nameAlkylated DNA repair protein alkB homolog 1
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:mitochondrion, C:nuclear euchromatin, F:chemoattractant activity, F:DNA-(apurinic or apyrimidinic site) lyase activity, F:ferrous iron binding, F:methylcytosine dioxygenase activity, P:developmental growth, P:DNA dealkylation involved in DNA repair, P:DNA demethylation, P:in utero embryonic development, P:negative regulation of neuron apoptotic process, P:neuron migration, P:neuron projection development, P:oxidative demethylation, P:placenta development, P:RNA repair, F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, P:DNA repair, C:mitochondrion, F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, P:RNA repair
UniProtComplete proteome, Dioxygenase, DNA damage, DNA repair, Iron, Lyase, Metal-binding, Mitochondrion, Multifunctional enzyme, Nucleus, Oxidoreductase, Polymorphism, Reference proteome, RNA repair
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.450.0000204RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium