CKDdb-logoCKDdb - Molecule ID A284F

geneAlg8, Gm1089
nameProbable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALG8_MOUSEQ6P8H8ENSMUSG00000035704381903Mm.279683608103, 608104

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:alpha-1,3-mannosyltransferase activity, P:mannosylation, P:protein N-linked glycosylation, C:integral to membrane, F:transferase activity, transferring hexosyl groups
UniProtComplete proteome, Endoplasmic reticulum, Glycosyltransferase, Membrane, Reference proteome, Transferase, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)2.430.01cDNA microarray19099603
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.472.04E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium