CKDdb-logoCKDdb - Molecule ID A282F

geneALG3, NOT, NOT56L
nameAlpha-1,3-mannosyltransferase ALG3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALG3_HUMANQ92685ENSG0000021416010195Hs.478481601110, 608750

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:alpha-1,3-mannosyltransferase activity, F:dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity, P:dolichol-linked oligosaccharide biosynthetic process, P:post-translational protein modification, P:protein N-linked glycosylation via asparagine, "C:endoplasmic reticulum, F:transferase activity, transferring hexosyl groups, P:metabolic process", C:integral to membrane, F:transferase activity, transferring hexosyl groups"
UniProtAlternative splicing, Complete proteome, Congenital disorder of glycosylation, Disease mutation, Endoplasmic reticulum, Glycosyltransferase, Membrane, Reference proteome, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.394.02E-05RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium