CKDdb-logoCKDdb - Molecule ID A280F

geneALG12, PP14673, PP3999
nameDolichyl-p-Man:Man(7)GlcNAc(2)-PP-dolichyl mannosyltransferase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALG12_HUMANQ9BV10ENSG0000018285879087Hs.526711607143, 607144

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:alpha-1,6-mannosyltransferase activity, F:dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity, P:dolichol-linked oligosaccharide biosynthetic process, P:post-translational protein modification, P:protein folding, P:protein N-linked glycosylation via asparagine, F:transferase activity, transferring glycosyl groups, P:metabolic process, C:integral to membrane, C:intrinsic to endoplasmic reticulum membrane, P:GPI anchor biosynthetic process, C:intrinsic to endoplasmic reticulum membrane, F:transferase activity, transferring glycosyl groups, P:GPI anchor biosynthetic process
UniProtComplete proteome, Congenital disorder of glycosylation, Disease mutation, Endoplasmic reticulum, Glycosyltransferase, Membrane, Polymorphism, Reference proteome, Transferase, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)2.740.0487203RNA microarray23935909

Compile date 08-10-2018© iMODE-CKD consortium