CKDdb-logoCKDdb - Molecule ID A278F

geneALS2CL
nameALS2 C-terminal-like protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AL2CL_HUMANQ60I27ENSG00000178038259173Hs.517937612402

Functions and classifications

GOC:cytoplasmic membrane-bounded vesicle, F:GTPase activator activity, F:Rho guanyl-nucleotide exchange factor activity, P:endosome organization, P:positive regulation of GTPase activity, P:protein localization, P:regulation of Rho GTPase activity, P:regulation of Rho protein signal transduction, C:intracellular
UniProtAlternative splicing, Complete proteome, Cytoplasm, GTPase activation, Polymorphism, Reference proteome, Repeat
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.370.0000802RNA microarray19698090
Exp20847290Homo sapiens30kidneyglomeruliGlomerulonephritis (FSGS + COLL)0.30.0438RNA microarray20847290
Exp20847290Homo sapiens30kidneyglomeruliGlomerulonephritis (FSGS + COLL)0.340.0972RNA microarray20847290
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.34< 0.05RNA microarray21752957
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)4.622.09E-08RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)7.30.004374RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium