CKDdb-logoCKDdb - Molecule ID A277F

geneAKT1S1, PRAS40
nameProline-rich AKT1 substrate 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKTS1_HUMANQ96B36ENSG0000020467384335Hs.515542610221

Functions and classifications

GOC:cytosol, C:nucleus, C:protein complex, P:epidermal growth factor receptor signaling pathway, P:Fc-epsilon receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:innate immune response, P:negative regulation of cell size, P:negative regulation of protein kinase activity, P:negative regulation of TOR signaling, P:neurotrophin TRK receptor signaling pathway, P:phosphatidylinositol-mediated signaling, P:regulation of neuron apoptotic process, C:cytosolic part, P:negative regulation of TOR signaling cascade, P:nerve growth factor receptor signaling pathway
UniProtAlternative splicing, Complete proteome, Cytoplasm, Phosphoprotein, Polymorphism, Reference proteome
PADBUK: unknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)3.860.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium