CKDdb-logoCKDdb - Molecule ID A276A

geneCBX8, PC3, RC1
nameChromobox protein homolog 8
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
CBX8_HUMANQ9HC52ENSG0000014157057332Hs.387258

Functions and classifications

GOC:heterochromatin, C:nuclear chromatin, C:PRC1 complex, C:ubiquitin ligase complex, F:methylated histone residue binding, F:single-stranded RNA binding, F:ubiquitin-protein ligase activity, P:histone ubiquitination, P:negative regulation of transcription from RNA polymerase II promoter, P:transcription, DNA-templated, C:nucleus, P:transcription, DNA-dependent, C:PcG protein complex
UniProt3D-structure, Chromatin regulator, Complete proteome, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repressor, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.000449RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.34< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium