CKDdb-logoCKDdb - Molecule ID A274A

geneCBX2
nameChromobox protein homolog 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CBX2_HUMANQ14781ENSG0000017389484733Hs.368410602770, 613080

Functions and classifications

GOC:heterochromatin, C:PRC1 complex, F:chromatin binding, F:DNA binding, P:cell differentiation, P:chromatin modification, P:development of primary sexual characteristics, P:negative regulation of transcription from RNA polymerase II promoter, P:transcription, DNA-templated, P:transcription, DNA-dependent
UniProt3D-structure, Alternative splicing, Chromatin regulator, Complete proteome, Differentiation, Disease mutation, DNA-binding, Nucleus, Reference proteome, Repressor, Sexual differentiation, Transcription, Transcription regulation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.420.0206RNA microarray19698090
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.160.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium