CKDdb-logoCKDdb - Molecule ID A273A

geneCasc5, Knl1
nameProtein CASC5
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CASC5_MOUSEQ66JQ7ENSMUSG0000002732676464Mm.202518604321, 609173

Functions and classifications

GOC:condensed chromosome kinetochore, C:nucleus, P:chromosome segregation, P:mitotic nuclear division, P:negative regulation of phosphatase activity, C:acrosomal vesicle, C:nucleus, P:attachment of spindle microtubules to kinetochore, P:negative regulation of phosphatase activity, P:protein localization to kinetochore, P:spindle assembly checkpoint, C:acrosomal vesicle, C:nucleus, P:attachment of spindle microtubules to kinetochore, P:negative regulation of phosphatase activity, P:protein localization to kinetochore, P:spindle assembly checkpoint
UniProtCell cycle, Cell division, Centromere, Chromosome, Chromosome partition, Complete proteome, Kinetochore, Mitosis, Nucleus, Phosphoprotein, Reference proteome, Repeat
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.470cDNA microarray21411733
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)4.6< 0.05RNA-seq23757392
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy)2.78< 0.05RNA-seq23757392
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.140.011083231LC-MS/MS24172336
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.410.0000113RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium